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Morgan PT, Breen L

Obese sedentary cohorts show partial neutralization of Gs-driven chronotropy by upregulated Gi coupling, producing a fundamentally different Hill curve than the intact-Gs signaling of lean responsive cohorts

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In the Wnt pathway, the key step of the Wnt pathway is the binding of the Wnt protein to the Frizzled receptor, and the nuclear redox protein (NRX) blocks Disheveled (DVL) and plays a negative regulatory role in the Wnt pathway (Yu et al., 2021)