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(PubMed) Ziegler D, Low PA, Freeman R, Tritschler H, Vinik AI

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Then, one optrode (16 tungsten wires surrounding a central optic fiber) was unilaterally implanted in the LH (from bregma (mm): AP -1.3, ML 1.0, and from dura: DV -5.5), and a subcutaneous catheter was inserted subcutaneously for tesofensine administration

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This combined 57.1% of patients with stable or improved disease had a mortality rate of only 1.5% which is exceptionally low for a population with baseline median MELD-3 of 16.4