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Promising therapeutic strategies include natural inhibitors (e.g., baicalin, silymarin, quercetin), pharmacological inhibitors like chlormethiazole, and gene-targeting approaches such as clustered regularly interspaced short palindromic repeat (CRISPR)-associated nuclease 9 (Cas9)-mediated knockdown in preclinical models [107, 110112]

At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta

In general, the evidence indicates that BPC-157 is safe for treating tendonitis and has few reported adverse effects in both preclinical and clinical studies

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