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Following an acute administration of EtOH (5 g/kg, i.p.), KO animals exhibited 30% and 50% less EtOH and AA accumulation in circulation, respectively, suggesting an increased capacity for liver EtOH and AA metabolism in KO mice

Most sports treat performance enhancers as they once did gambling: like an existential threat that undermines fairness and offends our shared humanity

Frataxin deficiency is associated with imbalances in iron-sulfur containing proteins, mitochondrial respiratory chain dysfunction and lower ATP production, and accumulation of iron in the mitochondria, which increases oxidative stress and oxidative damage to macromolecules of the respiratory chain (77)

Some protocols use higher doses or daily injection

Most of these side effects are mild, but, medical evaluation is recommended to avoid serious side effects and should be treated under supervision

Biochem Pharmacol 2000