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It can compromise the integrity of painstakingly synthesized peptides, introduce variables you can't account for, and ultimately render your data useless

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Using adenovirus-mediated gene transfer to study the effect of myeloperoxidase on plasma lipid levels, HDL structure and functionality in mice expressing human apoA-I forms

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Similarly, decreased EAAT1/EAAT2 (human homologs of GLAST/GLT1) mRNA and protein levels, as well as glutamate uptake, were observed in human astrocytes (Johnson et al., 2018)