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2 Material and methods This narrative literature review examines the use of SGLT-2 inhibitors and GLP-1 RAs in patients with T2DM and CVD
We used deuterium magnetic resonance spectroscopy (DMRS) to provide quantitative information about metabolic flux, fluorodeoxyglucose positron emission tomography (FDG-PET) to measure brain glucose metabolism, and resting state-functional MRI (rs-fMRI) to measure brain functional connectivity
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The proportion of patients with comorbidities associated with fracture risk such as T2D (26.7%), cardiac disease (16.3%), and liver disease (11.2%) was also reported
Additionally, ovarian tissues also exhibited an increase in GLP1R expression in tumor samples compared to normal tissues, although the difference was less pronounced than in the pancreas
Preliminary studies have hinted that this peptide might possibly mediate an increase in weight, potentially over 14lbs depending on test models
