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When lysine levels reach a desired concentration in the brain, the excess lysine is degraded by the GCDH

As mentioned before, free radicals have been found to react with macromolecules (lipids, proteins, DNA) within the cell, with one of the most frequent targets being the polyunsaturated fatty acids that largely comprise the cell membranes

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Piperlongumine (PL), an oxidative stress inducer, inhibits ZIKV replication in various cells, including the human brain microvascular, Vero, and human umbilical vein endothelial cells 129

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