In addition to the hormones GIP and glucagon, other hormones such as estrogen, peptide tyrosine tyrosine (PYY), gastrin, xenin, and fibroblast growth factor 21 can be good candidates to pair with GLP-1 and create dual agonists that have anti-diabetic and anti-obesity effects
This receptor is key to the activation of the GLP-1 molecule
If blood sugar or type 2 diabetes is part of the picture, the Type 2 Diabetes Posts collection may help you prepare more targeted questions
This highlights the importance of M&A for these emerging therapeutics in an investment thesis, as such trials are much more feasible for large pharma companies than for biotech startups
Its the active ingredient in Wegovy (approved specifically for weight loss) and Ozempic (approved for Type 2 diabetes, widely used off-label for weight management)
What do you think will be the next major breakthrough in obesity and diabetes treatment