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Ryan, MD, professor emerita at Pennington Biomedical Research Center, said the phase 3 data will help answer current unresolved questions, including GI tolerability with monthly dosing, whether the option of higher doses will translate into greater weight loss, whether berobenatide will have the same efficacy as other GLP-1s in improving cardiovascular and metabolic risk factors, and the effects of berobenatide on disease modification.

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After peaking at 817 drug-related deaths in 2017, the county has seen opioid deaths decline in recent years, a shift local officials credit to expanded naloxone access, follow-up care after overdoses and the crackdown on fraudulent sober homes